She said, 'Don't make others suffer for your personal hatred.' Shinseiki Evangelion : Season 1 Episode 12

Misato has been promoted to Major, but the celebration does not last long. A monstrous Angel appears in Earth orbit right when Gendo and Fuyutsuki are away, leaving her and the children to deal with a colossal kamikaze threatening to drop itself right on top of Tokyo-3.